潘长江

潘长江，博士，教授，硕士生导师

Email: pcj@cczu.edu.cn

教育经历

2003. 2～2006. 7，西南交通大学，材料学，工学博士

2000. 9～2002. 12，西南交通大学，材料学，工学硕士

1996. 9～2000. 7，四川轻化工学院，腐蚀与防护，工学学士

工作经历

2024.1～至今，常州大学，医学与健康工程学院，教授

2018.8～2023.12，淮阴工学院，机械与材料工程学院，教授

2012. 2～2018. 7，淮阴工学院，副教授（2013年8月）

2013. 3～2013. 9，美国特拉华大学及杜克大学访问学者。

2006. 7～2012. 1, 重庆大学生物工程学院，讲师

2007. 9～2009. 4，Friedrich-Schiller-University Jena, Germany，博士后

社会兼职

Frontiers in Bioengineering and Biotechnology，客座编辑（Guest Editor）

Metals，客座编辑（Guest Editor）

Frontiers in Materials，客座编辑（Guest Editor）

Frontiers in Bioengineering and Biotechnology副主编（Associate Editor），

BioMed Research International学术编辑（Academic Editor），

Smart Materials in Medicine编委

主要研究领域

生物医用材料

植入性医疗器械

药物递送系统

生物材料表界面

主要学术论文（*通讯作者）

[1] Jie Chen, Xuhui Liu, Qingxiang Hong, Lingjie Meng, Yan Ji, Lingtao Wang, Qiuyang Zhang, Jiafeng Lin, Changjiang Pan*. Synthesizing a multifunctional polymer to construct the catalytically NO-generating coating for improving corrosion resistance and biocompatibility of the magnesium alloy stent materials. Progress in Organic Coatings 186 (2024) 108058.

[2] Changjiang Pan*, Xuhui Liu, Qingxiang Hong, Jie Chen, Yuxin Cheng, Qiuyang Zhang, Lingjie Meng, Juan Dai, Zhongmei Yang, Lingren Wang. Recent advances in surface endothelialization of the magnesium allot stent materials. Journal of Magnesium and Alloys 11(2023) 48-77

[3] Wenfu Ma, Xuhui Liu, Minhui Yang, Qingxiang Hong, Lingjie Meng, Qiuyang Zhang*, Jie Chen, Changjiang Pan*. Fabrication of CO-releasing surface to enhance the blood compatibility and endothelialization of TiO2 nanotubes on titanium surface. Biomaterials Advances 149 (2023) 213393

[4] Qiuyang Zhang, Xuhui Liu, Wenfu Ma, Kunpeng Jia, Minhui Yang, Lingjie Meng, Lingtao Wang, Yan Ji, Jie Chen, Jiafeng Lin, Changjiang Pan*. A nitric oxide-catalytically generating carboxymethyl chitosan/sodium alginate hydrogel coating mimicking endothelium function for improving the biocompatibility. International Journal of Biological Macromolecules 253 (2023) 126727

[5] Lingjie Meng, Xuhui Liu, Qingxiang Hong, Yan Ji, Lingtao Wang, Qiuyang Zhang, Jie Chen*, Changjiang Pan*. Fabrication of Zn2+-loaded polydopamine coatings on magnesium alloy surfaces to enhance corrosion resistance and biocompatibility. Coatings 2023, 13, 1079

[6] Changjiang Pan*, Tao Liu, Ying Yang. Editorial: Advances in smart bioactive surfaces for wounding healing and tissue repair. Frontiers in Bioengineering and Biotechnology 2023, 11, 1140176.

[7] Qingxiang Hong, Hualan Zhou, Yuxin Cheng, Minhui Yang, Qiuyang Zhang, Sen Liu, Qingping Xiong, Changjiang Pan*. Synthesis of star 6-arm polyethylene glycol-heparin copolymer to construct anticorrosive and biocompatible coating on magnesium alloy surface. Front. Bioeng. Biotechnol. 2022, 10:853487.

[8] Lingjie Meng, Xuhui Liu, Li Liu, Qingxiang Hong, Yuxin Cheng, Fei Gao*, Jie Chen, Qiuyang Zhang*, Changjiang Pan*. Comparative investigation of the corrosion behavior and biocompatibility of the different chemical conversion coatings on the magnesium alloy surfaces. Metals 2022, 12, 1644.

[9] Feng Wu*, Yixuan Liu, Jing Xu, Changjiang Pan*, Bioinspired surface design for magnesium alloys with corrosion resistance. Metals 2022, 12, 1404.

[10] Lingren Wang*, Tao Gong, Weihua Ming, Xinglong Qiao, Wei Ye, Linna Zhang, Changjiang Pan*, One step preparation of multifunctional poly (ether sulfone) thin films with potential for wound dressing. Biomaterials Advances 2022, 136, 212758

[11] Qiuyang Zhang*, Hualan Zhou, Minhui Yang, Xuecong Tang, Qingxiang Hong, Zhongmei Yang, Sen Liu, Jie Chen, Guanghong Zhou, Changjiang Pan*. Fabrication and formation mechanism of gradient TiO2 nanotubes via bipolar anodization. Journal of Electroanalytical Chemistry 2022, 915, 116337.

[12] Youdong Hu, Hualan Zhou, Tingting Liu, Minhui Yang, Qiuyang Zhang, Changjiang Pan*, Jiafeng Lin*. Construction of mussel-inspired dopamine-Zn2+ coating on titanium oxide nanotube to improve hemocompatibility, cytocompatibility and antibacterial activity. Front. Bioeng. Biotechnol 2022, 10, 884258.

[13] Changjiang Pan*, Jingan Li, Juan Wang. Editorial: recent advances in biodegradable biomedical magnesium alloy. Front. Mater. 2022, 9:886092.

[14] Minhui Yang, Hualan Zhou, Yuxin Cheng, Qingxiang Hong, Jie Chen, Qiuyang Zhang, Changjiang Pan*. Incorporation of copper and strontium ions in TiO2 nanotubes via dopamine to enhance hemocompatibility and cytocompatibility. Nanotechnology Reviews 2022; 11: 1450-1463.

[15] Zhongmei Yang*, Jiaying Yan, Xuan Li, Sen Liu, Qiuyang Zhang, Yanchun Wei, Li Quan, Wei Ye, Changjiang Pan*. In situ carbonization combined with a low-temperature graphitization technique for preparation of CdS@graphitic carbon nanorods and their robust photocatalytic performance under visible light. ACS Sustainable Chemistry & Engineering 2022, 10 (10), 3311-3322.

[16] Changjiang Pan*, Tingting Liu, Ziqin Zhang, Xiaolei Zhang, Xinlong Qiao, Youdong Hu, Qiuyang Zhang, Zhongmei Yang, Preparation of chitosan-Zn²⁺ complex coating on polydopamine-modified TiO2 nanotubes to enhance osteoblast behaviors, Materials Letters 2021, 282, 128665.

[17] Sen Liu, Can Shen, Cheng Qian, Jianquan Wang, Zhihao Wang, Xuecong Tang, Qiuyang Zhang, Changjiang Pan* and Wei Ye*. A rapid dual-responsive releasing nano-carrier by decomposing the copolymer and reversing the core dissolution. Front. Bioeng. Biotechnol. 2021, 9, 784838.

[18]  Qiuyang Zhang, Li Zhang, Minhui Yang, Qingxiang Hong, Zhongmei Yang, Sen Liu, Qingping Xiong, and Changjiang Pan*, Construction of Chi(Zn/BMP2)/HA composite coating on AZ31B magnesium alloy surface to improve the corrosion resistance and biocompatibility, Nanotechnology Reviews 2021; 10: 870–882.

[19] Yuebin Lin, Ya Yang, Yongjun Zhao, Fan Gao, Xin Guo, Minhui Yang, Qingxiang Hong, Zhongmei Yang, Juan Dai, Changjiang Pan*. Incorporation of heparin/BMP2 complex on GOCS-modified magnesium alloy to synergistically improve corrosion resistance, anticoagulation, and osteogenesis. Journal of Materials Science: Materials in Medicine 2021, 32, 24.

[20] Changjiang Pan*, Yongjuan Zhao, Ya Yang, Minghui Yang, Qingxiang Hong, Zhongmei Yang, Qiuyang Zhang, Immobilization of bioactive complex on the surface of magnesium alloy stent material to simultaneously improve anticorrosion, hemocompatibility and antibacterial activities. Colloids and Surfaces B: Biointerfaces 2021, 199, 111541.

[21] Changjiang Pan*, Youdong Hu, Zhihao Gong, Ya Yang, Sen Liu, Li Quan, Zhongmei Yang, Yanchun Wei, Wei Ye. Improved blood compatibility and endothelialization of titanium oxide nanotube arrays on titanium surface by zinc doping. ACS Biomater. Sci. Eng. 2020, 6, 2072-2083.

[22] Changjiang Pan*, Tingting Liu, Ya Yang, Tao Liu, Zhihao Gong, Yanchun Wei, Li Quan, Zhongmei Yang, Sen Liu. Incorporation of Sr2+ and Ag nanoparticles into TiO2 nanotubes to synergistically enhance osteogenic and antibacterial activities for bone repair. Materials and Design, 196 (2020) 109086.

[23] Feng Zhao, Ya Yang, Yongjuan Zhao, Yanchun Wei, Li Quan, Changjiang Pan*, Design and mechanical properties simulation of fish scale-like intracranial thrombectomy stent, Journal of Materials Research 2020, 35(18), 2416-2426.

[24] Fan Gao, Youdong Hu, Guicai Li, Sen Liu, Li Quan, Zhongmei Yang, Yanchun Wei, Changjiang Pan*. Layer-by-layer deposition of bioactive layers on magnesium alloy stent materials to improve corrosion resistance and biocompatibility. Bioactive Materials 2020, 5(3): 611-623.

[25] Zhihao Gong, Youdong Hu, Fan Gao, Li Quan, Tao Liu, Tao Gong, Changjiang Pan*. Effects of diameters and crystals of titanium dioxide nanotube arrays on blood compatibility and endothelial cell behaviors. Colloids and Surfaces B: Biointerfaces 184 (2019) 110521.

[26] Fan Gao, Youdong Hu, Zhihao Gong, Tao Liu, Tao Gong, Sen Liu, Chao Zhang, Li Quan, B. Kavenndran, Changjiang Pan*. Fabrication of chitosan/heparinized graphene oxide multilayer coating to improve corrosion resistance and biocompatibility of magnesium alloys. Materials Science & Engineering C 104 (2019) 109947.

[27] Zhiming Li, Jiazhi Ma, Rongguo Li, Xueqiong Yin*, Wenyuan Dong, Changjiang Pan. Fabrication of a blood compatible composite membrane from chitosan nanoparticles, ethyl cellulose and bacterial cellulose sulfate. RSC Adv., 2018, 8, 31322-31330.

[28] Xiangyang Li, Peng Gao, Jianying Tan, Kaiqin Xiong, Manfred F. Maitz, Changjiang Pan, Hongkai Wu, Yin Chen, Zhilu Yang, Nan Huang. Assembly of metal-phenolic/catecholamine networks for synergistically anti-inflammatory, antimicrobial, and anticoagulation coatings. ACS Appl. Mater. Interfaces 2018, 10, 40844-40853.

[29] Weikang Song, Qinhuan Zeng, Xueqiong Yin*, Li Zhu, Tao Gong, Changjiang Pan*. Preparation and anticoagulation properties of heparin-like electrospun membranes from carboxymethyl chitosan and bacterial cellulose sulfate. International Journal of Biological Macromolecules 2018, 120, 1396-1405.

[30] Gong Tao, Liu Tao, Zhang Lincai, Ye We, Guo Xin, Wang Lingren, Quan Li, Pan Changjiang*. Design redox-sensitive drug-loaded nanofibers for bone reconstruction. ACS Biomaterials Science & Engineering 2018; 4(1): 240-247.

[31] Lin-Cai Zhang, Mingzhu Xu, You-Dong Hu, Fan Gao, Tao Gong, Tao Liu, Xia Li, Chang-Jiang Pan*. Biofunctionization of biodegradable magnesium alloy to improve the in vitro corrosion resistance and biocompatibility. Applied Surface Science 2018, 451, 20-31.

[32] Yu-Jie Zhang, You-Dong Hu, Chang-Jiang Pan*, Heng-Quan Liu, Yue-Bin Lin, Tao Gong, Tao Liu. Improving corrosion resistance and biocompatibility of magnesium alloy by combining chemical treatment with biomolecules immobilization. J. Biomater. Tissue Eng. 2017, 7(11), 1102-1113.

[33] Lingren Wang, Min He, Tao Gong, Xiang Zhang, Lincai Zhang, Tao Liu, Wei Ye, Changjiang Pan*, Changsheng Zhao*. Introducing multiple bio-functional groups on the poly(ether sulfone) membrane substrate to fabricate an effective antithrombotic bio-interface. Biomaterials Science 2017, 5, 2416-2426.

[34] Li Quan, Hongyan Ding, Changjiang Pan*, Yanchun Wei, Zhigang Xie*. Revealing membrane permeability of polymersomes through fluorescence enhancement. Colloids and Surfaces B: Biointerfaces 2018, 161, 156-161.

[35] Tao Liu, Xin Wang, Xiaohan Tang, Tao Gong, Wei Ye, Changjiang Pan*, Hongyan Ding, Xun Luo, Xia Li*, Qing Mei Wang*. Surface modification with ECM-inspired SDF-1/Laminin-loaded nanocating for vascular would healing. ACS Appl. Mater. Interfaces 2017, 9, 30373-30386.

[36] Tao Liu, Xia Li, Shihui Liu, Xiaohan Tang, Xin Wang, Tao Gong, Youdong Hu, Hongyan Ding, Xun Luo, Changjiang Pan*, Qingmei Wang. Surface modification with micropatterned heparin/poly-L-lysine nanoparticles to direct platelet and endothelial cell behavior. J. Biomater. Tissue Eng. 2017, 7, 962-968.

[37] Changjiang Pan*, Youdong Hu, Yu Hou, Tao Liu, Yuebin Lin, Wei Ye, Yanhua Hou, Tao Gong. Corrosion resistance and biocompatibility of magnesium alloy modified by alkali heating treatment followed by the immobilization of poly (ethylene glycol), fibronectin and heparin. Materials Science and Engineering C 2017, 70, 438-449.

[38] Chang-Jiang Pan*, Li-Qun Pang, Yu Hou, Yue-Bin Lin, Tao Gong, Tao Liu, Wei Ye, Hong-Yan Ding. Improving corrosion resistance and biocompatibility of magnesium alloy by sodium hydroxide and hydrofluoric acid treatments. Applied Science-Basel 2017, 7(1), 33.

[39] Chang-Jiang Pan*, Yu Hou, Ya-Nan Wang, Tao Liu, Tao Gong, Yue-Bin Lin, Ling-Ren Wang, Wei Ye. Biofunctionalisation of magnesium alloys by successive immobilization of poly(ethylene glycol), fibronectin and heparin. Bioinspired, Biomimetic and Nanobiomaterials 2017, 6(3): 131-141

[40] Changjiang Pan*, Hengquan Liu, Tao Liu, Shijie Zhou. A metal coating of copper-titanium as potential biomaterials. Integrated Ferroelectrics 2017, 179(1): 56-62.

[41] Chang-Jiang Pan*, Li-Qun Pang, Fei Gao, Ya-Nan Wang, Tao Liu, Wei Ye, Yan-Hua Hou. Anticoagulation and endothelial cell behaviors of heparin-loaded graphene oxide coating on titanium surface. Materials Science and Engineering C 2016, 63, 333-340.

[42] Chang-Jiang Pan*, Yu Hou, Ya-Nan Wang, Fei Gao, Tao Liu, Yan-Hua Hou, Yu-Fu Zhu, Wei Ye, Ling-Ren Wang. Effects of self-assembly of 3-phosphonopropionic acid, 3-aminopropyltrimethoxysilane and dopamine on the corrosion behaviors and biocompatibility of a magnesium alloy. Materials Science and Engineering C 2016, 67, 132-143.

[43] Pan Changjiang*, Zhang Bingbing, Zhang Man, Dong Yunxiao, Ding Hongyan. Effects of BMP-2 patterns on bovine chondrocytes adhesion and alignment. Journal of Wuhan University of Technology-Mater. Sci. Ed. 2014, 29: 1057-1062

[44] 潘长江*，侯彦华，刘恒全. ECM蛋白微图形对成骨及软骨细胞生长行为的调控. 稀有金属材料与工程，2014, 43, 296-301

[45] Chang-Jiang Pan*, Heng-Quan Liu, Ya-Nan Wang, Hong-Yan Ding. Phase transformation and mechanical behaviors of vena cava filter modified by deposition of copper-titanium coating. Material Research Bulletin 2014, 60, 217-221.

[46] Chang-Jiang Pan*, Yan-Hua Hou, Bin-Bin Zhang, Yun-Xiao Dong, Hong-Yan Ding, Blood compatibility and interaction with endothelial cells of titanium modified by sequential immobilization of poly (ethylene glycol) and heparin, Journal of Materials Chemistry B, 2(7), 892-902, 2014.

[47] Chang-Jiang Pan*, Yan-Hua Hou, Bin-Bin Zhang, Lin-Cai Zhang, Fabrication of anticoagulation layer on titanium surface by sequential immobilization of poly (ethylene glycol) and albumin, Bio-Medical Materials and Engineering, 24, 781-787, 2014.

[48] Chang-Jiang Pan*, Yan-Hua Hou, Heng-Quan Liu, Hong-Yan Ding, Yun-Xiao Dong, Improved anticoagulation of titanium by sequential immobilization of oligo(ethylene glycol) and 2-methacryloyloxyethyl phosphorylcholine, Colloids and Surfaces B, 2013, 112, 508-512.

[49] Chang-Jiang Pan*, Yan-Hua Hou, Hong-Yan Ding, Yun-Xiao Dong, Enhancing anticoagulation and endothelial cell proliferation of titanium surface by sequential immobilization of poly(ethylene glycol) and collagen, Applied Surface Science, 287, 443-450, 2013.

[50] Chang-Jiang Pan*, Hao Qin, Yu-Dong Nie, Hong-Yan Ding, Control of osteoblast cells adhesion and spreading by microcontact printing of extracellular matrix protein patterns, Colloids and Surfaces B: Biointerfaces, 104, 18-26, 2013.

[51] Chang-Jiang Pan*, Hong-Yan Ding, Yun-Xiao Dong, Extracellular matrix protein patterns guide human chondrocytes adhesion and alignment characterized by vimentin and matrilin-3, Colloids and Surfaces B: Biointerfaces, 102, 730– 736, 2013.

[52] Chang-Jiang Pan*, Yun-Xiao Dong, Yao-Yao Zhang, Yu-Dong Nie, Chang-Hong Zhao, Yuan-Liang Wang, Enhancing the antibacterial activity of biomimetic HA coatings by incorporation of norvancomycin, Journal of Orthopaedic Science, 16, 105-113, 2011.

[53] 潘长江*，聂煜东，董云肖, 原子转移自由基聚合在生物材料中的应用, 材料导报, 25(23), 80-84, 2011

[54] 潘长江*, 董云肖,  聂煜东,  王远亮, 生物材料表面蛋白质微图形对人体软骨细胞形态及蛋白表达的影响,  生物化学与生物物理进展,  37, 1296-1302, 2010

[55] Chang-Jiang Pan*, Yu-Dong Nie, Microcontact printing of BMP-2 and its effect on human chondrocytes behavior, Applied Surface Science, 256, 1878-1882, 2010.

[56] 潘长江*, 聂煜东, 蔡开勇, 王远亮, 钛表面接枝壳聚糖诱导羟基磷灰石涂层的形成, 材料导报, 24(9), 39-41, 2010

[57] Chang-Jiang Pan*, Jin Wang, Nan Huang, Preparation, characterization and in vitro anticoagulation of emodin-eluting controlled biodegradable coating stents, Colloids and Surfaces B: Biointerfaces, 77, 155-160, 2010.

[58] Chang-Jiang Pan, Jia-Ju Tang, Ya-Jun Weng, Jin Wang, Nan Huang*. Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents. Colloids and Surfaces B: Biointerfaces 2009; 73: 199-206.

[59] C.J. Pan, J.J. Tang, Z.Y. Shao, J wang, N Huang*. Improved blood compatibility of rapamycin-eluting stent by incorporating curcumin. Colloids and surfaces B: Biointerfaces 2007; 59: 105-111.

[60] C. J. Pan, Z.Y. Shao, J.J Tang, J Wang, N Huang*. In vitro studies of platelet adhesion, activation, and protein adsorption on curcumin-eluting biodegradable stent materials. Journal of Biomedical materials research Part A 2007; 82A(3): 740-746.

[61] Pan C. J, Tang J.J, Weng Y.J, Y, Wang J, Huang N*. Preparation and characterization of rapamycin-loaded PLGA coating stent. Journal of materials science: Materials in Medicine. 2007；18:2193–2198.

[62] Ch. J. Pan, J.J. Tang, Y.J. Weng, J. Wang, N. Huang*. Preparation, characterization and anticoagulation of curcumin-eluting controlled biodegradable coating stents. Journal of controlled release 2006; 116: 42-49.

[63] C. J Pan, Wang. J, Huang. N*, Sun. H. The hemocompatibility of poly (ethylene terephthalate, PET) films grafted poly(ethylene glycol) by plasma surface modification. Key engineering materials, 2005；288-289:339

[64] 潘长江，黄楠*，刘睿睿，王进，孙鸿. 不同有机单体等离子体聚合的对比研究. 高分子材料科学与工程2005; 21（2）：89-92

[65] 潘长江，唐家驹，王进，黄楠*. 血管支架内再狭窄的机理研究进展. 中国介入影像与治疗学2005; 2（4）：314-317

[66] 潘长江，王进，孙鸿等. 等离子体表面改性涤纶材料的血浆蛋白吸附与血小板粘附行为研究. 生物医学工程学杂志2004; 21（4）：536-540

[67] 潘长江，黄楠*，刘睿睿等. 等离子体聚合工艺对聚合沉积速率的影响. 真空科学与技术学报2004; 24（6）：455-458

[68] 潘长江，王进，黄楠*. 血管支架内再狭窄的研究进展. 中国生物医学工程学报2004; 23（2）：152-156

[69] 潘长江，王进，黄楠*等. 等离子体表面接枝改性聚对苯二甲酸乙二醇酯的血液相容性研究. 功能材料2003; 34（3）：468-470

授权发明专利

[1] 潘长江，刘恒全，刘涛，龚韬，一种多功能血管支架的制备方法，ZL201810938556.3

[2] Chang-Jiang Pan, Tao Liu, Tao Gong, Lincai Zhang, Wei Ye. Method for preparing chitosan/heparinized graphene oxide composite multilayer film on surface of medical magnesium alloy. US 10729821B1（美国），美国发明专利

[3] 潘长江，高凡，林岳宾、贡志昊，刘涛，龚韬，张临财，一种表面载肝素的镁合金材料及其制备方法和应用，ZL201810269659.5

[4] 潘长江，权莉，林岳宾，贡志昊，刘涛，龚韬，一种表面载Zn²⁺的镁合金材料及其制备方法和应用，ZL201810269856.7

[5] 潘长江，徐静，贡志昊，刘涛，权莉，高凡，龚韬，表面载金属离子的Ca-P涂层的镁合金材料及其制备方法和应用，ZL201810440747.7

[6] 潘长江，刘恒全，刘涛，龚韬，一种在钛合金表面构建NO催化型纳米涂层的方法，ZL201611046169.6

[7] 潘长江，刘涛，龚韬，张临财，叶玮，一种在医用镁合金表面制备壳聚糖/肝素化氧化石墨烯复合多层膜的方法，ZL201710297089.6

[8] 潘长江，刘涛，龚韬，在生物材料表面制备载肝素及Cu²⁺的介孔硅纳米颗粒涂层的方法，ZL201710364589.7

[9] 潘长江，张瑜杰，丁红燕，刘涛，龚韬，王亚楠，一种医用镁合金表面改性方法，ZL201710294673.6

[10] 潘长江，崔景民，一种可延期回收的血栓滤器及其制作方法，ZL201711129443.0

[11] 潘长江，刘恒全，龚韬，基于热压印技术制备3D多孔生物支架的方法，ZL201611144533.2

[12] 潘长江，王亚楠，刘涛，侯彦华，张临财. 生物材料的表面改性方法, ZL201410291528

[13] 潘长江，董云肖，丁红燕，张兵兵, 促细胞生长的抗生物污染的材料表面处理方法, ZL201210233083.X

[14] 潘长江，谯兴龙，张子沁，常克明，陈露，杨忠美，一种协同提高镁合金耐蚀性能和生物相容性的多功能表面改性方法，ZL202010567160.X