郭佳

郭佳，博士，讲师

E-mail：guojia@cczu.edu.cn

教育经历：

l  2006-2011：中国农业大学微生物分子生物学，获得博士学位；

l  2002-2006：中国农业大学微生物分子生物学，获得学士学位。

工作经历：

l  2017—：常州大学生物医学工程与健康科学研究院，讲师；

l  2015—2017：江南大学细胞生物学，讲师；

l  2012.—2015：江南大学细胞生物学，博士后。

研究方向：

l  细胞生物学

l  分子生物学

发表论文：

[1].Jia Guo#, Jinlei Zhao#, Lili Li, Zhi Chen, Ying Wen, Jilun Li. (2010) The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis. Mol Genet Genomics 283:123–133.

[2].Jia Guo#, Xuan Zhang#, Zhi Chen, Ying Wen, Jilun Li. (2013) A novel TetR family transcriptional regulator, SAV576, negatively controls avermectin biosynthesis in Streptomyces avermitilis. PloS One 8(8): e71330.

[3].Jia Guo, Xuan Zhang, Zhi Chen, Ying Wen, Jilun Li. (2014) Two adjacent and similar TetR family transcriptional regulator genes, SAV577 and SAV576, co-regulate avermectin production in Streptomyces avermitilis. PloS One 9(6): e99224.

[4].Jia Guo, Zengqi Tan, Wei Lu, Ganglong Yang, Feng Guan. (2014) Alteration of N-glycans and expression of its related glycogenes in epithelial-mesenchymal transition of HCV29 bladder epithelial cells. Molecules 19(12), 20073-20090.

[5].Jia Guo, Bo Song, Xiang Li, Chenhui He, Ganglong Yang, Feng Guan. (2015) Down-regulation of gangliotetraosylceramide (Gg4) and β3GalT4 gene expression by Smads during TGF-β-induced epithelial-mesenchymal transition. Mol Med Rep 11(3): 2241-2247.

[6].Jia Guo#, Yicheng Wang#, Bo Song, Xin Wang, Ganglong Yang, Feng Guan. (2015) Identification and functional characterization of intracellular sialidase NeuA3 from Streptomyces avermitilis. Process Biochem 50(5): 752-758.

[7].Jia Guo#, Changmei Liu#, Xiaoman Zhou, Xiaoqiang Xu, Linhong Deng, Xiang Li, Feng Guan. (2017) Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells. Int J Mol Sci 18, 1528; doi:10.3390/ijms18081528.

[8].Zengqi Tan, Wei Lu, Xiang Li, Ganglong Yang, Jia Guo, Hanjie Yu, Zheng Li, Feng Guan. (2014) Altered N-glycan expression profile in epithelial-to-mesenchymal transition of NMuMG cells revealed by an integrated strategy using mass spectrometry and glycogene and lectin microarray analysis. J Proteome Res 13 (6): 2783-2795.

[9].Feng Guan, Xiang Li, Jia Guo, Ganglong Yang, Xiang Li. (2015) Ganglioside-magnetosome complex formation enhances uptake of gangliosides by cellsInternational. Int J Nanomed 10: 1-12.

[10].     Ganglong Yang, Zengqi Tan, Wei Lu, Jia Guo, Hanjie Yu, Jingmin Yu, Chengwen Sun, Xiaowei Qi, Zheng Li, Feng Guan. (2015) Quantitative glycome analysis of N-glycan patterns in bladder cancer vs. normal bladder cells using an integrated strategy. J Proteome Res 14，639-653.

授权专利：

[1].关锋、李想、杨刚龙、郭佳、刘昌梅，一种细菌纳米磁小体–凝集素复合物及其制备方法与应用，专利号：ZL201510075253.X